Aldosterone antagonists in the treatment of poorly controlled and resistant arterial hypertension – results of the newest PATHWAY-2 trial Review article
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Abstract
Treatment of hypertension in many cases requires the use of several antihypertensive agents. Current guidelines determine in which groups of patients specific groups of antihypertensive drugs should be preferred, they also give recommendations on particular combinations of 2 antihypertensive agents. PATHWAY-2 study was the first study to establish a treatment algorithm in patients with resistant hypertension and to define the place of spironolactone in the treatment. The present paper summarizes the current state of knowledge on these issues.
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