OphthaTherapy https://journalsmededu.pl/index.php/ophthatherapy <p>"OphthaTherapy. Therapies in Ophthalmology" (abbr.: OphthaTherapy) is a peer-reviewed scientific quarterly publishing papers in: ophthalmology, ophthalmic surgery (including minimally invasive surgery and laser therapy), pharmacological treatment of eye diseases, including glaucoma, as well as work in the contactology. The journal is on the list of the Polish Ministry of Science and Higher Education. For publishing the article, the author receives 20 points.<br>We encourage you to submit: original papers, review articles, case reports, rapid communication, research letters, hypotheses, meeting proceedings, letter to the editor. We guarantee fast publication. There are no submission or processing charges.</p> <p><strong>"OphthaTherapy" accepts submissions in English only. Other language versions may be published as additional ones.</strong><br><br><strong><span lang="en-GB">e-ISSN: </span></strong><span lang="en-GB">2543-9987</span><span lang="en-GB">&nbsp;</span><strong><span lang="en-GB"> &nbsp; &nbsp; &nbsp;ISSN: 2353-7175 &nbsp; &nbsp; &nbsp; DOI: </span></strong><span lang="en-GB">10.24292/01.OT<br><br></span><strong><span lang="en-GB">Indexed in:&nbsp;</span></strong><span lang="en-GB">Polish Journals Master List: 20 points&nbsp;<br></span><span lang="en-GB">&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;Google Scholar<br></span>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Polish Scientific Journal Database</p> Medical Education sp. z o.o. en-US OphthaTherapy 2353-7175 <p><strong>Copyright: © Medical Education sp. z o.o.</strong> License allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.</p> <p><em>Address reprint requests to: Medical Education, Marcin Kuźma (<a href="mailto:marcin.kuzma@mededu.pl">marcin.kuzma@mededu.pl</a>)</em></p> The ultrabiomicroscopic examination in diagnostics, treatment and management of patients with glaucoma https://journalsmededu.pl/index.php/ophthatherapy/article/view/1092 <p>Ultrabiomicroscopic (UBM) examination is a powerful diagnostic tool that can assist in the management and treatment of many patients. It is especially helpful in the case of glaucoma and damage to the optic nerve. We can successfully treat patients only if we are aware of the disease cause. Although UBM examination cannot replace a complete clinical examination (including dynamic gonioscopy), it is a great supplement that can confirm many diagnoses.</p> Grzegorz Jasina Marta Misiuk-Hojło Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 185 191 10.24292/01.OT.300920.1 Blepharitis: a comprehensive look at a common disease https://journalsmededu.pl/index.php/ophthatherapy/article/view/1054 <p>Chronic blepharitis is a common, chronic inflammatory disease of the external eye whose detailed epidemiology is difficult to determine. Also, the role of individual etiological factors, such as demodex infestation, remains undefined. The diagnosis is based on a comprehensive physical examination with a thorough ophthalmological examination, supplemented with possible additional examinations. The therapy lasts long and usually does not lead to full recovery, requires patience and systematic commitment from patients. The constantly expanding therapeutic range is not reimbursed by public healthcare in most countries.</p> Michał Karaszewski Marta Misiuk-Hojło Joanna Przeździecka-Dołyk Jan Gnus Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0 2020-08-31 2020-08-31 7 3 192 202 10.24292/01.OT.310820 Clinical evaluation of the effect of topical bevacizumab on morphology and function of filtering bleb with failure symptoms https://journalsmededu.pl/index.php/ophthatherapy/article/view/1091 <p><strong>Objectives</strong>: Evaluation of bevacizumab drops in patients undergoing trabeculectomy in order to inhibit postoperative wound healing.<br><strong>Material and methods</strong>: A total of 53 patients treated surgically for glaucoma. The anti-glaucoma procedures with the creation of a filtering bleb were performed. The patients developed early postoperative bleb insufficiency qualifying them for the use of bevacizumab drops. Thirty were completely statistically analyzed; intraocular pressure and slit lamp examinations were performed and the bleb was assessed according to the MBGS. Additionally, photographs of the filtering blebs were made, which were used for bleb morphological analysis.<br><strong>Results</strong>: Total success, after 6 months, without using anti-glaucoma drugs (intraocular pressure &lt; 18 mmHg and a decrease in baseline intraocular pressure by 30%) was observed in 18 patients (60%). Partial success, after 6 months, without using anti-glaucoma drugs (decrease in baseline intraocular pressure by 30%) was achieved in 19 patients (63.3%).<br><strong>Conclusions</strong>: Bevacizumab is an effective and safe adjunctive therapy with topical steroids for the treatment of early postoperative filtering bleb insufficiency as it reduces innervation on the bleb surface. Evaluation of the mean surface of bleb vessels on photographs, using ImageJ (Wayne Rasband), correlates with MBGS evaluation of filtering blebs.</p> Anna Kuna Tomasz Żarnowski Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 203 212 10.24292/01.OT.300920.2 Fuchs dystrophy: insight into disease pathophysiology and treatment https://journalsmededu.pl/index.php/ophthatherapy/article/view/1090 <p>Fuchs endothelial corneal dystrophy (FECD) is a bilateral, progressive disease originating in corneal endothelial cells. Fuchs endothelial corneal dystrophy slowly progresses, causing endothelial cell loss, subsequent corneal stromal and epithelial edema, leading to visual acuity impairment and ocular pain. Fuchs endothelial corneal dystrophy was first documented more than a hundred years ago – in 1910, when Viennese ophthalmologist Ernst Fuchs reported 13 elderly patients with bilateral central clouding. Since then, there have been a far-reaching progress in terms of pathogenesis, knowledge of etiological factors, as well as progress in diagnosis and treatment. Despite that, there are still many questions remaining unanswered, especially in the field of the genetic basis of FECD and the molecular pathomechanisms. The aim of this review is to present and discuss clinical, genetic, pathophysiologic, diagnostic and therapeutic aspects of this common corneal dystrophy. The article also focuses on innovative methods of imagining including high-resolution optical coherence tomography. Moreover, we highlight and discuss the development of traditional surgical treatment options and new minimally invasive techniques such as descemetorhexis without endothelial keratoplasty (DWEK) and Rho-associated kinase inhibitor (ROCK inhibitors) eye drops.</p> Anna Micińska Anna Nowińska Adam Sendecki Edward Wylęgała Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 213 224 10.24292/01.OT.300920.3 Anti-VEGF drugs in treatment of retinopathy of prematurity https://journalsmededu.pl/index.php/ophthatherapy/article/view/1087 <p>Retinopathy of prematurity is a serious disease that can lead to retinal detachment and vision loss. Vascular endothelial growth factors (VEGF) play a key role in the pathogenesis of this disease. The gold standard of treatment used since the 1990s is laser coagulation of non-vascularized retina. Anti-VEGF drugs introduced in recent years administered as intravitreal injections neutralize excess VEGF factors. The main advantage of these drugs is very fast action, very short and uncomplicated administration procedure, full field of view expected. Drugs, however, are absorbed into the bloodstream, which can affect the physiological maturation of internal organs in a child born prematurely. Another important problem is the appearance of late recurrences of retinopathy, even several months after the injection. These drugs should be used prudently, especially in patients with retinopathy in zone I.</p> Wojciech Hautz Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 225 231 10.24292/01.OT.300920.8 Therapy of congenital glaucoma https://journalsmededu.pl/index.php/ophthatherapy/article/view/1072 <p>The primary therapy of all forms of primary and secondary congenital glaucoma is surgical. In the last few decades, the options for customized surgical approach to different types of childhood glaucoma have significantly developed. In particular, circumferential trabeculotomy has shown some superiority over conventional trabeculotomy and is now also used to treat secondary congenital glaucoma. Goniotomy is still a valid alternative. Tube implants in childhood glaucoma still need improvements.</p> Franz Grehn Esther Hoffmann Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 232 238 10.24292/01.OT.300920.4 Modified technique of phacoemulsification and its impact on expected postoperative parameters https://journalsmededu.pl/index.php/ophthatherapy/article/view/1093 <p>Phacoemulsification is a common surgical procedure performed in every ophthalmology department. Good postoperative visual acuity is the result of many pre-, intra and postoperative components, including correct morphometric measurement of the eyeball and calculation of the artificial lens power using an appropriate calculation formula. The ophthalmologist should have extensive knowledge of the potential impact of surgical technique modifications on the postoperative visual acuity, as performing additional intraoperative manipulations may be associated with unexpected postoperative ametropia and need to correct the refractive value of the implanted intraocular lens.</p> Magdalena Skorek Piotr Jurowski Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 239 245 10.24292/01.OT.300920.5 Ultrasound ciliary plasty in refractory glaucoma treatment – a medium-term follow-up study https://journalsmededu.pl/index.php/ophthatherapy/article/view/1095 <p><strong>Objectives</strong>: To assess the efficacy and safety of ultrasound ciliary plasty (UCP) for treating refractory glaucoma during one year follow-up.<br><strong>Material and methods</strong>: A total of 57 patients (37 F, 20 M; mean age: 67.6 years) with primary and secondary refractory glaucoma were enrolled to undergo UCP. The inclusion criteria for the study were: ≥ 18 years, uncontrolled open-angle glaucoma (IOP &gt; 21 mmHg), contraindication to incisional glaucoma surgery, intolerance to glaucoma medications despite well-controlled IOP. The exclusion criteria were: pregnancy, age &lt; 18 years, IOP &gt; 30 mmHg, angle-closure glaucoma and neovascular glaucoma. Complete ophthalmic examinations were performed preoperatively and as well as 1 week and 1, 3, 6, 12 months postoperatively. An IOP reduction of 20% or &gt; 5 mmHg as compared to the baseline value was considered as successful treatment. Complete success was defined as cessation of antiglaucoma medications.<br><strong>Results</strong>: The mean IOP at the last follow-up was reduced by 26.9%. The success rate was 87.7% and the complete success rate was 12.3%. The mean ± SD values of the number of antiglaucoma medications were: 4.0 ± 0.9, 0.9 ± 1.1, 0.9 ± 1.1, 1.1 ± 1.1, 1.8 ± 1.4, 2.1 ± 1.4, 2.4 ± 1.4 (p &lt; 0.001 for all values), respectively. The best-corrected logMAR visual acuities were: 0.37 ± 0.46, 0.47 ± 0.45 (p = 0.003), 0.46 ± 0.45 (p = 0.004), 0.31 ± 0.37 (p = 0.151), 0.36 ± 0.45 (p = 0.880), 0.39 ± 0.47 (p = 0.504), respectively. Following the procedure, choroid detachment was observed in three patients (5.3%) and macular in two patients (3.5%). No other major intraoperative or postoperative complications occurred.<br><strong>Conclusion</strong>: Ultrasound ciliary plasty is a safe and well-tolerated procedure in medium-term follow-up. Further studies with a larger group of patients and longer follow-up are needed to confirm these results.</p> Bartłomiej Bolek Edward Wylęgała Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 246 254 10.24292/01.OT.300920.6 The use of laser therapy in retinal diseases. Part II https://journalsmededu.pl/index.php/ophthatherapy/article/view/1073 <p>Retinal diseases account for the vast majority of ophthalmologic disorders. Over the past years, laser-based approach has been successfully used. Despite introduction of other potentially innovative, beneficial and successful therapeutic methods, lasers are still considered the gold standard. In this review, we discuss the spectrum of currently prevailing laser methods and we give a new insight into novel perspectives and techniques regarding laser management of retinal disorders. This paper is divided into three sections. The current one consists of a literature review that investigates the existing knowledge in laser management of diabetic retinopathy, diabetic macular edema and vascular retinal disorders. Finally, it outlines the principles guiding laser treatment of retinal tears, retinal degeneration, retinopathy of prematurity, age-related macular degeneration and other retinal diseases.</p> Katarzyna Warzecha Agnieszka Tronina Erita Filipek Copyright (c) 2020 Medical Education https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-09-30 2020-09-30 7 3 255 261 10.24292/01.OT.300920.7 The role of social media in ophthalmology: a narrative review https://journalsmededu.pl/index.php/ophthatherapy/article/view/1052 <p>Social media have played an increasing role in medicine with potential applications for both physicians and patients. This trend has also impacted clinical and surgical practice in ophthalmology in a wide range of subspecialties to promote scientific research findings, provide further tools for teaching, and ease communication between ophthalmologists across the globe improving patient care. However, social media have certain limitations that need to be overcome to ensure their reliability and quality for physicians and patients. This article provides a review of the current applications and pitfalls of social media in ophthalmology.</p> Nuno Moura-Coelho Copyright (c) 2020 Medical Education sp. z o.o. https://creativecommons.org/licenses/by-nc-nd/4.0/ 2020-08-14 2020-08-14 7 3 262 266 10.24292/01.OT.3009140820